Original articles

2014
Deneberg S, Kanduri M, Ali D, Bengtzen S, Karimi M, Qu Y, Kimby E, Mansouri L, Rosenquist R, Lennartsson A#, Sören Lehmann#. MicroRNA-34b/c on chromosome 11q23 is aberrantly methylated in chronic lymphocytic leukemi. Epigenetics in press.

Forrest ARR, Kawaji H, Rehli M, Baillie JK, de Hoon MJL, Haberle V, Lassmann T, Kulakovskiy IV, Lizio M, Itoh M et al. (Ekwall K. number 61 and Lennartsson A. number 136 out of 250 authors) (2014): A promoter level mammalian expression atlas. Nature. 507, 462–470, doi: 10.1038/nature13182. Mar 27.

Andersson R, Gebhard C, Miguel-Escalada I, Hoof I, Boyd M, Bornholdt J, Chen Y, Zhao X, Schmidl C, Suzuki T, Ntini E, Arner E, Valen E, Li K, Schwarzfischer L, Glatz D, Raithel J, Lilje B, Rapin N, Otzen Bagger F, Jørgensen M, Andersen P, Bertin N, Rackham O, Burroughs A.M, Baillie J.K, Ishizu Y, Shimizu Y, Furhata E, Maeda S, Negishi Y, Mungall C, Meehan T.F, Lassmann T, Itoh M, Kawaji H, Kondo N, Kawai J, Lennartsson A, Daub C.O, Heutink P, Hume D.A, Jensen T., Suzuki H, Hayashizaki Y, Müller F, Forrest A., Carninci P., Rehli M*, Sandelin A.* An atlas of active enhancers across human cell types and tissues. Nature 507, 455–461, doi: 10.1038/nature12787. Epub 2014 Mar 27.

Rönnerblad M, Andersson R, Olofsson T, Douagi I, Karimi M, Lehmann S, Hoof I, de Hoon M, Itoh M, Nago-Sato S, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest AR, Sandelin A, the FANTOM consortium, Ekwall K*, Arner E*, Lennartsson A* Analysis of the DNA methylome and transcriptome in granulopoiesis reveal timed changes and dynamic enhancer methylation. Blood. Epub 2014 Mar 27.

Prasad P#, Rönnerblad M#, Arner E, Itoh M, Kawaji H, Lassmann T, Daub C, Forrest A.R.R, the FANTOM consortium, Lennartsson A*, Ekwall K*. High-throughput transcription profiling identifies putative epigenetic regulators of hematopoiesi. Blood. Epub 2014 Mar 27.

2013
Sandén C, Ageberg M, Petersson J, Lennartsson A, Gullberg U. Forced expression of the DEK-NUP214 fusion protein promotes proliferation dependent on upregulation of mTOR. BMC Cancer. 2013 Sep 27;13(1):440.

Vidovic K, Ullmark T, Rosberg B, Lennartsson A, Olofsson T, Nilsson B, Gullberg U. Leukemia associated mutant Wilms' tumor gene 1 protein promotes expansion of human hematopoietic progenitor cells. Leuk Res. 2013 Jul 18. PMID: 23871158. Link

Melas PA, Lennartsson A, Vakifahmetoglu-Norberg H, Wei Y, Aberg E, Werme M, Rogdaki M, Mannervik M, Wegener G, Brené S, Mathé AA, Lavebratt C. Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression. Transl Psychiatry. 2013 May 7;3:e255. PMID: 23652932. Link

2011
Deneberg S, Guardiola P, Lennartsson A, Qu Y, Gaidzik VI, Blanchet O, Karimi M, Bengtzen S, Nahi H, Uggla B, Tidefelt U, Höglund M, Paul C, Ekwall K, Doehner K, Lehmann S. Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks. Blood. 2011 Sep 29. Full text

Melas P.A., Rogdaki M., Lennartsson A., Björk K., Qi H., Witasp A., Werme M., Wegener G., Greengard P., Mathé A.A., Svenningsson P., Lavebratt C. "Antidepressant Treatment is Associated with Epigenetic Alterations in the Promoter of P11 in a Genetic Model of Depression". Int J Neuropsychopharmacol. 2011 Jun 20:1-11. Pubmed.

Previous publications
Vidovic K., Svensson E., Nilsson B., Thuresson B., Lennartsson A., Gullberg U. "The Wilms' tumour gene 1 protein represses expression of the tumour suppressor Interferon Response Factor 8 in human hematopoietic and leukemic cells." Leukemia 2010 May;24(5):992-1000.

The FANTOM consortium and RIKEN Genome Exploration Research Group "A complex transcriptional network controls growth arrest and differentiation in a human myeloid leukemia cell line." Nat Genet. 2009 May;41(5):553-62. Full text

Lennartsson A., Vidovic K., Gullberg U. All-Trans Retinoic Acid-Induced Expression of Bactericidal/Permeability-Increasing Protein (BPI) in Myeloid Cells Correlates to Binding of C/EBPbeta and C/EBPepsilon to the BPI Promoter J Leukoc Biol. 2006 Jul;80(1):196-203. Full text

Canny G., Brennan C., Lennartsson A., Gullberg U., Cario E., Levy O., Serhan C.N., Colgan S.P. Functional and Biochemical Characterization of Epithelial Bactericidal / Permeability-Increasing Protein (BPI) Am J Physiol Gastrointest Liver Physiol. 2005 Nov 10. Full text

Lennartsson A., Garwicz D., Lindmark A., Gullberg U The Proximal Promoter of Human Cathepsin G Conferring Myeloid-Specific Expression includes C/EBP, c-myb and PU.1 Binding Sites Gene. 2005 Aug 15;356:193-202. Full text

Lennartsson A., Pieters K., Vidovic K.,Gullberg U. A murine antibacterial orthologue to human Bactericidal/Permeability Increasing protein (BPI) is expressed in testis, epididymis and bone marrow J Leukoc Biol. 2005 Mar;77(3):369-77. Full text

Garwicz D., Lennartsson A., Jacobsen SEW., Gullberg U., Lindmark A. Biosynthetic profiles of neutrophil serine proteases in a human bone marrow-derived cellular myeloid differentiation model Haematologica, 2005 Jan; 90 (1):38-44. Full text

Lennartsson A., Pieters K., Ullmark T., Vidovic K., Gullberg U. AML-1, PU.1, and Sp3 regulate expression of human bactericidal/permeability increasing protein. Biochem Biophys Res Commun. 2003 Nov 28;311(4):853-63. Full text

Review article
Lennartsson A., Ekwall K. Histone modification patterns and epigenetic codes. Biochim Biophys Acta. 2009 Sep;1790(9):863-8. Full text