Peter Svensson lab




2014
Sadeghi L*, Siggens L*, Svensson JP#, Ekwall K#. Centromeric H2B monoubiquitination promotes non-coding transcription and chromatin integrity. Nat Struct Mol Biol. 21, 236–243. doi: 10.1038/nsmb.2776

2013
Svensson JP, Quiros Pesudo L, McRee SK, Adeleye Y, Carmichael P, Samson LD. Genomic phenotyping by barcode sequencing broadly distinguishes between alkylating agents, oxidizing agents, and non-genotoxic agents, and reveals a role for aromatic amino acids in cellular recovery after quinone exposure. PLoS One. 2013 Sep 9;8(9):e73736. doi: 10.1371/journal.pone.0073736.

Vahey MD, Quiros Pesudo L, Svensson JP, Samson LD, Voldman J. Microfluidic genome-wide profiling of intrinsic electrical properties in Saccharomyces cerevisiae. Lab Chip. 2013 May 9. PMID: 23661198. Link

2012
Pointner J*, Persson J*, Prasad P*, Norman-Axelsson U, Strålfors A, Khorosjutina O, Krietenstein N, Svensson JP, Ekwall K, Korber P. CHD1 remodelers space nucleosomes in vitro and link regular arrays to 5’ ends of genes in S. pombe. EMBO J. 31(23):4388-403. Link

Choi ES, Strålfors A, Castillo AG, Svensson JP, Pidoux AL, Ekwall K and Allshire RC. Factors which promote integrity of H3 chromatin during transcription prevent promiscuous deposition of CENP-ACnp1 in fission yeast. PLoS Genetics 8(9): e1002985. Link

Ryan CJ*, Roguev A*, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, Edelmann W, Keogh MC, Greene D, Tang C, Cunningham P, Shokat KM, Cagney G, Svensson JP, Guthrie C, Espenshade PJ, Ideker T, Krogan NJ. Hierarchical modularity and the evolution of genetic interactomes across species. Molecular Cell 46(5): 691. Link

Svensson JP, Fry RC, Wang E, Somoza LA, Samson LD. Identification of novel human damage response proteins targeted through yeast orthology. Plos One 7(5): e37368. Link

2011
Svensson JP, Quiros Pesudo L, Fry RC, Adeleye YA, Carmichael P, Samson LD. Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Systems Biology 5:157. Link

Sadeghi L, Bonilla C, Strålfors A, Ekwall K, Svensson JP. Podbat: A Novel Genomic Tool Reveals Swr1-independent H2A.Z Incorporation at Gene Coding Sequences Through Epigenetic Meta Analysis. Plos Comput Biol 7(8): e1002163. doi:10.1371/journal.pcbi.1002163. Link

Durand-Dubief M, Svensson JP, Persson J, Ekwall K. Topoisomerases, chromatin and transcription termination. Transcription. 2011 March;2(2):66-70. Link

2008
Fry RC*, Svensson JP*, Valiathan C*, Wang E, Hogan BJ, Bhattacharya S, Bugni JM, Whittaker CA, Samson LD. Genomic predictors of interindividual differences in response to DNA damaging agents. Genes Dev. 2008 Oct 1;22(19):2621-6. Link

2007
Rusyn I, Fry RC, Begley TJ, Klapacz J, Svensson JP, Ambrose M, Samson LD. Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates. Plos One. 2007 Nov 28;2(11):e1252. Link

Fry RC, Navasumrit P, Valiathan C, Svensson JP, Hogan BJ, Luo M, Bhattacharya S, Kandjanapa K, Soontararuks S, Nookabkaew S, Mahidol C, Ruchirawat M, Samson LD. Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers. Plos Genet. 2007 Nov;3(11):e207. Link

Kruse JJ*, Svensson JP*, Huigsloot M*, Giphart-Gassler M, Schoonen WG, Polman JE, Jean Horbach G, van de Water B, Vrieling H. A portrait of cisplatin-induced transcriptional changes in mouse embryonic stem cells reveals a dominant p53-like response. Mutat Res. 2007 Apr 1;617(1-2):58-70. Link

van Bezooijen RL, Svensson JP, Eefting D, Visser A, van der Horst G, Karperien M, Quax PH, Vrieling H, Papapoulos SE, ten Dijke P, Löwik CW. Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation. J Bone Miner Res. 2007 Jan;22(1):19-28. Link

2006
Svensson JP, Stalpers LJ, Esveldt-van Lange RE, Franken NA, Haveman J, Klein B, Turesson I, Vrieling H, Giphart-Gassler M. Analysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicity. Plos Med. 2006 Oct;3(10):e422. Link

2005
Svensson JP, de Menezes RX, Turesson I, Giphart-Gassler M, Vrieling H. Dissecting systems-wide data using mixture models: application to identify affected cellular processes. BMC Bioinformatics. 2005 Jul 14;6:177. Link

Jahangir Tafrechi RS, Svensson PJ, Janssen GM, Szuhai K, Maassen JA, Raap AK. Distinct nuclear gene expression profiles in cells with mtDNA depletion and homoplasmic A3243G mutation. Mutat Res. 2005 Oct 15;578(1-2):43-52. Link

Boerma M, van der Wees CG, Vrieling H, Svensson JP, Wondergem J, van der Laarse A, Mullenders LH, van Zeeland AA. Microarray analysis of gene expression profiles of cardiac myocytes and fibroblasts after mechanical stress, ionising or ultraviolet radiation. BMC Genomics. 2005 Jan 18;6(1):6. Link

*,#equal contribution